SHROOM2 antibody (AA 427-1138) (Fluoro488)

Catalog No. ABIN8037089

This Rabbit Polyclonal antibody specifically detects SHROOM2 in FACS. It exhibits reactivity toward Human.

Quick Overview for SHROOM2 antibody (AA 427-1138) (Fluoro488) (ABIN8037089)

Target: SHROOM2 (Shroom Family Member 2 (SHROOM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHROOM2 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-SHROOM2 Antibody (Fluoro488)

Binding Specificity: AA 427-1138

Purpose: Anti-SHROOM2 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SHROOM2 recombinant protein (Position: R427-H1138).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SHROOM2

Target: SHROOM2 (Shroom Family Member 2 (SHROOM2))

Alternative Name: SHROOM2

Background:

Background: Shroom family member 2 is a protein that in humans is encoded by the SHROOM2 gene. This gene represents the human homolog of Xenopus laevis apical protein (APX) gene, which is implicated in amiloride-sensitive sodium channel activity. It is expressed in endothelial cells and facilitates the formation of a contractile network within endothelial cells. Depletion of this gene results in an increase in endothelial sprouting, migration, and angiogenesis. This gene is highly expressed in the retina, and is a strong candidate for ocular albinism type 1 syndrome. Alternatively spliced transcript variants have been found for this gene.

Gene Full Name: shroom family member 2

Gene ID: 357

UniProt: Q13796

Pathways: Cell-Cell Junction Organization, Asymmetric Protein Localization