SHROOM2 antibody (AA 427-1138) (HRP)

Catalog No. ABIN8037093

The Rabbit Polyclonal anti-SHROOM2 antibody is suitable to detect SHROOM2 in samples from Human. It has been validated for ELISA, WB and IHC.

Quick Overview for SHROOM2 antibody (AA 427-1138) (HRP) (ABIN8037093)

Target: SHROOM2 (Shroom Family Member 2 (SHROOM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHROOM2 antibody is conjugated to HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SHROOM2 Antibody (HRP)

Binding Specificity: AA 427-1138

Purpose: Anti-SHROOM2 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SHROOM2 recombinant protein (Position: R427-H1138).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SHROOM2

Target: SHROOM2 (Shroom Family Member 2 (SHROOM2))

Alternative Name: SHROOM2

Background:

Background: Shroom family member 2 is a protein that in humans is encoded by the SHROOM2 gene. This gene represents the human homolog of Xenopus laevis apical protein (APX) gene, which is implicated in amiloride-sensitive sodium channel activity. It is expressed in endothelial cells and facilitates the formation of a contractile network within endothelial cells. Depletion of this gene results in an increase in endothelial sprouting, migration, and angiogenesis. This gene is highly expressed in the retina, and is a strong candidate for ocular albinism type 1 syndrome. Alternatively spliced transcript variants have been found for this gene.

Gene Full Name: shroom family member 2

Gene ID: 357

UniProt: Q13796

Pathways: Cell-Cell Junction Organization, Asymmetric Protein Localization