SSR1 antibody (AA 53-286) (Fluoro647)

Catalog No. ABIN8037362

This Rabbit Polyclonal antibody specifically detects SSR1 in FACS. It exhibits reactivity toward Human, Mouse, Rat and Monkey.

Quick Overview for SSR1 antibody (AA 53-286) (Fluoro647) (ABIN8037362)

Target: SSR1 (Signal Sequence Receptor, alpha (SSR1))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSR1 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-SSR1 Antibody (Fluoro647)

Binding Specificity: AA 53-286

Purpose: Anti-TRAP alpha/TRAPA/SSR1 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SSR1 recombinant protein (Position: E53-E286).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SSR1

Target: SSR1 (Signal Sequence Receptor, alpha (SSR1))

Alternative Name: SSR1

Background:

Background: Translocon-associated protein subunit alpha is a protein that in humans is encoded by the SSR1 gene. The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: signal sequence receptor subunit 1

Gene ID: 6745

UniProt: P43307

Pathways: ER-Nucleus Signaling