STAP1 antibody (AA 2-282) (HRP)

Catalog No. ABIN8037568

The HRP-conjugated Rabbit Polyclonal anti-STAP1 antibody (ABIN8037568) specifically detects STAP1 in WB, IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for STAP1 antibody (AA 2-282) (HRP) (ABIN8037568)

Target: STAP1 (Signal Transducing Adaptor Family Member 1 (STAP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAP1 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-STAP1 Antibody (HRP)

Binding Specificity: AA 2-282

Purpose: Anti-STAP-1/STAP1 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human STAP-1/STAP1 recombinant protein (Position: M2-E282).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for STAP1

Target: STAP1 (Signal Transducing Adaptor Family Member 1 (STAP1))

Alternative Name: STAP1

Background:

Background: Signal-transducing adaptor protein 1 is a protein that in humans is encoded by the STAP1 gene. The protein encoded by this gene contains a proline-rich region, a pleckstrin homology (PH) domain, and a region in the carboxy terminal half with similarity to the Src Homology 2 (SH2) domain. This protein is a substrate of tyrosine-protein kinase Tec, and its interaction with tyrosine-protein kinase Tec is phosphorylation-dependent. This protein is thought to participate in a positive feedback loop by upregulating the activity of tyrosine-protein kinase Tec. Variants of this gene have been associated with autosomal-dominant hypercholesterolemia (ADH), which is characterized by elevated low-density lipoprotein cholesterol levels and in increased risk of coronary vascular disease. Alternative splicing results in multiple transcript variants.

Gene Full Name: signal transducing adaptor family member 1

Gene ID: 26228

UniProt: Q9ULZ2