SIPA1 antibody (AA 21-1034) (Fluoro594)

Catalog No. ABIN8037610

The Fluoro594-conjugated Rabbit Polyclonal anti-SIPA1 antibody (ABIN8037610) specifically detects SIPA1 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SIPA1 antibody (AA 21-1034) (Fluoro594) (ABIN8037610)

Target: SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIPA1 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-SIPA1 Antibody (Fluoro594)

Binding Specificity: AA 21-1034

Purpose: Anti-SIPA1 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human SIPA1 shares 89% amino acid (aa) sequence identity with mouse SIPA1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SIPA1 recombinant protein (Position: D21-L1034). Human SIPA1 shares 89% amino acid (aa) sequence identity with mouse SIPA1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SIPA1

Target: SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))

Alternative Name: SIPA1

Background:

Background: The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.

Gene Full Name: signal-induced proliferation-associated 1

Gene ID: 6494

UniProt: Q96FS4

Pathways: Response to Water Deprivation