SIPA1 antibody (AA 21-1034)

Catalog No. ABIN8037616

The Rabbit Polyclonal anti-SIPA1 antibody (ABIN8037616) specifically detects SIPA1 in ELISA, WB, IF, FACS and ICC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SIPA1 antibody (AA 21-1034) (ABIN8037616)

Target: SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIPA1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Grade: Carrier-free

Product Details anti-SIPA1 Antibody

Binding Specificity: AA 21-1034

Purpose: Anti-SIPA1 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human SIPA1 shares 89% amino acid (aa) sequence identity with mouse SIPA1.

Characteristics: Anti-SIPA1 Antibody. Tested in WB, ICC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SIPA1 recombinant protein (Position: D21-L1034). Human SIPA1 shares 89% amino acid (aa) sequence identity with mouse SIPA1.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SIPA1

Target: SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))

Alternative Name: SIPA1

Background:

Background: The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.

Gene Full Name: signal-induced proliferation-associated 1

Molecular Weight: 130 kDa

Gene ID: 6494

UniProt: Q96FS4

Pathways: Response to Water Deprivation