SSB antibody (AA 6-283) (Fluoro488)

Catalog No. ABIN8037906

The Rabbit Polyclonal anti-SSB antibody is suitable to detect SSB in samples from Human. It has been validated for FACS.

Quick Overview for SSB antibody (AA 6-283) (Fluoro488) (ABIN8037906)

Target: SSB (Sjogren Syndrome Antigen B (SSB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSB antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-SSB Antibody (Fluoro488)

Binding Specificity: AA 6-283

Purpose: Anti-SSB Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SSB recombinant protein (Position: D6-L283).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SSB

Target: SSB (Sjogren Syndrome Antigen B (SSB))

Alternative Name: SSB

Background:

Background: Sjgren syndrome type B antigen (SS-B) also known as Lupus La protein is a protein that in humans is encoded by the SSB gene. The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.

Gene Full Name: small RNA binding exonuclease protection factor La

Gene ID: 6741

UniProt: P05455