SLAMF6 antibody (AA 22-332) (APC)

Catalog No. ABIN8037944

This Rabbit Polyclonal antibody specifically detects SLAMF6 in FACS. It exhibits reactivity toward Human.

Quick Overview for SLAMF6 antibody (AA 22-332) (APC) (ABIN8037944)

Target: SLAMF6 (SLAM Family Member 6 (SLAMF6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLAMF6 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-SLAMF6 Antibody (APC)

Binding Specificity: AA 22-332

Purpose: Anti-SLAMF6 Antibody APC Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human SLAMF6 shares 43.1% amino acid (aa) sequence identity with mouse SLAMF6.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SLAMF6 recombinant protein (Position: Q22-V332). Human SLAMF6 shares 43.1% amino acid (aa) sequence identity with mouse SLAMF6.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SLAMF6

Target: SLAMF6 (SLAM Family Member 6 (SLAMF6))

Alternative Name: SLAMF6

Background:

Background: SLAM family member 6 is a protein that in humans is encoded by the SLAMF6 gene. The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Full Name: SLAM family member 6

Gene ID: 114836

UniProt: Q96DU3