SLAMF6 antibody (AA 22-332)

Catalog No. ABIN8037947

This Rabbit Polyclonal antibody specifically detects SLAMF6 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for SLAMF6 antibody (AA 22-332) (ABIN8037947)

Target: SLAMF6 (SLAM Family Member 6 (SLAMF6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLAMF6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-SLAMF6 Antibody

Binding Specificity: AA 22-332

Purpose: Anti-SLAMF6 Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human SLAMF6 shares 43.1% amino acid (aa) sequence identity with mouse SLAMF6.

Characteristics: Anti-SLAMF6 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SLAMF6 recombinant protein (Position: Q22-V332). Human SLAMF6 shares 43.1% amino acid (aa) sequence identity with mouse SLAMF6.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SLAMF6

Target: SLAMF6 (SLAM Family Member 6 (SLAMF6))

Alternative Name: SLAMF6

Background:

Background: SLAM family member 6 is a protein that in humans is encoded by the SLAMF6 gene. The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Full Name: SLAM family member 6

Molecular Weight: 60 kDa

Gene ID: 114836

UniProt: Q96DU3