SMAD9 antibody (AA 153-235) (Fluoro647)

Catalog No. ABIN8038057

The Fluoro647-conjugated Rabbit Polyclonal anti-SMAD9 antibody (ABIN8038057) specifically detects SMAD9 in FACS. The antibody is reactive with Mouse and Rat samples.

Quick Overview for SMAD9 antibody (AA 153-235) (Fluoro647) (ABIN8038057)

Target: SMAD9 (SMAD Family Member 9 (SMAD9))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMAD9 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-SMAD9 Antibody (Fluoro647)

Binding Specificity: AA 153-235

Purpose: Anti-Smad9 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Mouse Smad9 shares 59.2%,96.4% amino acid (aa) sequence identity with human,rat Smad9,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Smad9 recombinant protein (Position: Q153-H235). Mouse Smad9 shares 59.2% and 96.4% amino acid (aa) sequence identity with human and rat Smad9, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SMAD9

Target: SMAD9 (SMAD Family Member 9 (SMAD9))

Alternative Name: Smad9

Background:

Background: Mothers against decapentaplegic homolog 9 also known as SMAD9, SMAD8, and MADH6 is a protein that in humans is encoded by the SMAD9 gene. This gene encodes a member of a family of proteins that act as downstream effectors of the bone morphogenetic protein (BMP) signaling pathway. The encoded protein is phosphorylated by BMP receptors, which stimulates its binding to SMAD4 and translocation into the nucleus, where it functions as a regulator of transcription. Activity of this protein is important for embryonic development. Mutation of this gene results in defects in pulmonary vasculature.

Gene Full Name: SMAD family member 9

Gene ID: 55994

UniProt: Q9JIW5