SMAD9 antibody (AA 153-235)

Catalog No. ABIN8038058

This Rabbit Polyclonal antibody specifically detects SMAD9 in WB and ELISA. It exhibits reactivity toward Mouse and Rat.

Quick Overview for SMAD9 antibody (AA 153-235) (ABIN8038058)

Target: SMAD9 (SMAD Family Member 9 (SMAD9))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMAD9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Product Details anti-SMAD9 Antibody

Binding Specificity: AA 153-235

Purpose: Anti-Smad9 Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Mouse Smad9 shares 59.2%,96.4% amino acid (aa) sequence identity with human,rat Smad9,respectively.

Characteristics: Anti-Smad9 Antibody. Tested in WB, ELISA applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Smad9 recombinant protein (Position: Q153-H235). Mouse Smad9 shares 59.2% and 96.4% amino acid (aa) sequence identity with human and rat Smad9, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SMAD9

Target: SMAD9 (SMAD Family Member 9 (SMAD9))

Alternative Name: Smad9

Background:

Background: Mothers against decapentaplegic homolog 9 also known as SMAD9, SMAD8, and MADH6 is a protein that in humans is encoded by the SMAD9 gene. This gene encodes a member of a family of proteins that act as downstream effectors of the bone morphogenetic protein (BMP) signaling pathway. The encoded protein is phosphorylated by BMP receptors, which stimulates its binding to SMAD4 and translocation into the nucleus, where it functions as a regulator of transcription. Activity of this protein is important for embryonic development. Mutation of this gene results in defects in pulmonary vasculature.

Gene Full Name: SMAD family member 9

Molecular Weight: 55 kDa

Gene ID: 55994

UniProt: Q9JIW5