SNAIL antibody (AA 1-170) (Fluoro594)

Catalog No. ABIN8038571

This Rabbit Polyclonal antibody specifically detects SNAIL in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SNAIL antibody (AA 1-170) (Fluoro594) (ABIN8038571)

Target: SNAIL (SNAI1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNAIL antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-SNAIL Antibody (Fluoro594)

Binding Specificity: AA 1-170

Purpose: Anti-SNAIL/SNAI1 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SNAIL/SNAI1 recombinant protein (Position: M1-K170).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SNAIL

Target: SNAIL (SNAI1)

Alternative Name: SNAI1

Background:

Background: The Drosophila embryonic protein SNAI1, commonly known as Snail, is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. And it is located in 16q24.3. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. It is studied that SNAIL gene may show a role in recurrence of breast cancer by downregulating E-cadherin and inducing anepithelial to mesenchymal transition.

Gene Full Name: snail family transcriptional repressor 1

Gene ID: 6615

UniProt: O95863

Pathways: Negative Regulation of intrinsic apoptotic Signaling