SNAI3 antibody (Middle Region) (Cy3)

Catalog No. ABIN8038590

The Rabbit Polyclonal anti-SNAI3 antibody is suitable to detect SNAI3 in samples from Human. It has been validated for FACS.

Quick Overview for SNAI3 antibody (Middle Region) (Cy3) (ABIN8038590)

Target: SNAI3 (Snail Homolog 3 (SNAI3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNAI3 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-SNAI3 Antibody (Cy3)

Binding Specificity: Middle Region

Purpose: Anti-SNAI3 Antibody Cy3 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by two amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human SNAI3, different from the related mouse sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SNAI3

Target: SNAI3 (Snail Homolog 3 (SNAI3))

Alternative Name: SNAI3

Background:

Background: SNAI3 is a member of the SNAIL gene family, named for the Drosophila snail gene, which plays roles in mesodermal formation during embryogenesis. SNAI3 gene, was located between KIAA0233 gene and CBFA2T3 gene in human chromosome 16q24.3, a region affected in breast cancer, gastric cancer, hepatocellular carcinoma, ovarian cancer, and therapy-related myeloid leukemia with t (16,21) (q24,q22) translocation. Human SNAI3 gene was found to encode 292-amino-acid polypeptide with the N-terminal SNAG domain and five zinc finger domains. And Human SNAI3 mRNA was expressed in skin melanotic melanoma, lung epidermoid carcinoma, and germ cell tumor. Because SNAG zinc-finger proteins are transcriptional repressors implicated in carcinogenesis and embryogenesis, SNAI3 gene might be a potent target of pharmacogenomics in the field of oncology and regenerative medicine.

Gene Full Name: snail family transcriptional repressor 3

Sequence Similarities: Belongs to the snail C2H2-type zinc-finger protein family.

Gene ID: 333929

UniProt: Q3KNW1