SLC22A5 antibody (C-Term) (Fluoro488)

Catalog No. ABIN8039574

The Rabbit Polyclonal anti-SLC22A5 antibody is suitable to detect SLC22A5 in samples from Mouse and Rat. It has been validated for FACS.

Quick Overview for SLC22A5 antibody (C-Term) (Fluoro488) (ABIN8039574)

Target: SLC22A5 (Solute Carrier Family 22 Member 5 (SLC22A5))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC22A5 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-SLC22A5 Antibody (Fluoro488)

Binding Specificity: C-Term

Purpose: Anti-Solute carrier family 22 member 5/SLC22A5 Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related rat sequence by two amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Solute carrier family 22 member 5, different from the related rat sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SLC22A5

Target: SLC22A5 (Solute Carrier Family 22 Member 5 (SLC22A5))

Alternative Name: SLC22A5

Background:

Background: Solute carrier family 22 (organic cation/carnitine transporter), member 5, also called SLC22A5 or OCTN2 is a membrane transport protein associated with primary carnitine deficiency. This gene is mapped to 5q31.1. Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy.

Gene Full Name: solute carrier family 22 (organic cation transporter), member 5

Gene ID: 20520

UniProt: Q9Z0E8