Sonic Hedgehog antibody (N-Term) (Fluoro550)

Catalog No. ABIN8040813

The Rabbit Polyclonal anti-Sonic Hedgehog antibody is suitable to detect Sonic Hedgehog in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for Sonic Hedgehog antibody (N-Term) (Fluoro550) (ABIN8040813)

Target: Sonic Hedgehog (SHH)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sonic Hedgehog antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-Sonic Hedgehog Antibody (Fluoro550)

Binding Specificity: N-Term

Purpose: Anti-Sonic Hedgehog/SHH Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: identical to the related rat,mouse sequences.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Sonic Hedgehog, identical to the related rat and mouse sequences.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Sonic Hedgehog

Target: Sonic Hedgehog (SHH)

Alternative Name: SHH

Background:

Background: The mouse, chicken, and zebrafish Shh homologs are highly conserved. SHH expression was not detected in adult tissues examined. However, it was expressed in fetal intestine, liver, lung, and kidney. SHH gene is mapped to 7q. SHH mutations are not a frequent cause of isolated oral clefts.

Gene Full Name: sonic hedgehog signaling molecule

Sequence Similarities: Belongs to the hedgehog family.

Gene ID: 6469

UniProt: Q15465

Pathways: Hedgehog Signaling, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development