SORD antibody (AA 8-357) (Fluoro647)

Catalog No. ABIN8040863

This Mouse Monoclonal antibody specifically detects SORD in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SORD antibody (AA 8-357) (Fluoro647) (ABIN8040863)

Target: SORD (Sorbitol Dehydrogenase (SORD))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This SORD antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Clone: 12B10G2

Product Details anti-SORD Antibody (Fluoro647)

Binding Specificity: AA 8-357

Purpose: Anti-Sorbitol Dehydrogenase/SORD Antibody (monoclonal, 12B10G2) Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Sorbitol Dehydrogenase/SORD recombinant protein (Position: N8-P357).

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SORD

Target: SORD (Sorbitol Dehydrogenase (SORD))

Alternative Name: SORD

Background:

Background: Sorbitol dehydrogenase is an enzyme that in humans is encoded by the SORD gene. Sorbitol dehydrogenase (SORD) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase, makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications. The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.

Gene Full Name: sorbitol dehydrogenase

Gene ID: 6652

UniProt: Q00796