Sorting Nexin 2 antibody (AA 1-506) (Biotin)

Catalog No. ABIN8040953

This Rabbit Polyclonal antibody specifically detects Sorting Nexin 2 in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Sorting Nexin 2 antibody (AA 1-506) (Biotin) (ABIN8040953)

Target: Sorting Nexin 2 (SNX2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sorting Nexin 2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Sorting Nexin 2 Antibody (Biotin)

Binding Specificity: AA 1-506

Purpose: Anti-SNX2 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human SNX2 shares 98% amino acid (aa) sequence identity with mouse SNX2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SNX2 recombinant protein (Position: M1-K506). Human SNX2 shares 98% amino acid (aa) sequence identity with mouse SNX2.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Sorting Nexin 2

Target: Sorting Nexin 2 (SNX2)

Alternative Name: SNX2

Background:

Background: This gene belongs to the sorting nexin family whose members contain the phosphoinositide-binding phox (PX) domain. The encoded protein is a component of the retromer complex which plays a role in protein sorting in the endocytic pathway. This protein may form oligomeric complexes with other family members. Alternate splicing results in multiple transcript variants of this gene. Pseudogenes associated with this gene are located on chromosomes 1 and 7.

Gene Full Name: sorting nexin 2

Gene ID: 6643

UniProt: O60749