SP1 antibody (AA 384-603) (HRP)

Catalog No. ABIN8041115

This Mouse Monoclonal antibody specifically detects SP1 in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for SP1 antibody (AA 384-603) (HRP) (ABIN8041115)

Target: SP1 (Sp1 Transcription Factor (SP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SP1 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 3C4C3

Product Details anti-SP1 Antibody (HRP)

Binding Specificity: AA 384-603

Purpose: Anti-SP1 Antibody (monoclonal, 3C4C3) HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human SP1 recombinant protein (Position: Q384-A603).

Isotype: IgG1

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SP1

Target: SP1 (Sp1 Transcription Factor (SP1))

Alternative Name: SP1

Background:

Background: Transcription factor Sp1, also known as specificity protein 1* is a protein that in humans is encoded by the SP1 gene. The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: Sp1 transcription factor

Gene ID: 6667

UniProt: P08047

Pathways: Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction