Spectrin beta Chain, Erythrocyte (SPTB) (AA 703-2137) antibody (HRP)

Catalog No. ABIN8041381

The HRP-conjugated Rabbit Polyclonal anti-Spectrin beta Chain, Erythrocyte antibody (ABIN8041381) specifically detects Spectrin beta Chain, Erythrocyte in WB, IHC and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for Spectrin beta Chain, Erythrocyte (SPTB) (AA 703-2137) antibody (HRP) (ABIN8041381)

Target: Spectrin beta Chain, Erythrocyte (SPTB)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details

Binding Specificity: AA 703-2137

Purpose: Anti-beta 1 Spectrin/SPTB Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human beta 1 Spectrin/SPTB recombinant protein (Position: M703-Y2137).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details

Target: Spectrin beta Chain, Erythrocyte (SPTB)

Alternative Name: SPTB

Background:

Background: Spectrin beta chain, erythrocyte is a protein that in humans is encoded by the SPTB gene. This locus encodes a member of the spectrin gene family. Spectrin proteins, along with ankyrin, play a role in cell membrane organization and stability. The protein encoded by this locus functions in stability of erythrocyte membranes, and mutations in this gene have been associated with spherocytosis type 2, hereditary elliptocytosis, and neonatal hemolytic anemia. Alternatively spliced transcript variants have been described.

Gene Full Name: spectrin beta, erythrocytic

Gene ID: 6710

UniProt: P11277

Pathways: Regulation of Actin Filament Polymerization