FAM33A antibody (N-Term) (APC)

Catalog No. ABIN8041759

The APC-conjugated Rabbit Polyclonal anti-FAM33A antibody (ABIN8041759) specifically detects FAM33A in FACS. The antibody is reactive with Human samples.

Quick Overview for FAM33A antibody (N-Term) (APC) (ABIN8041759)

Target: FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM33A antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-FAM33A Antibody (APC)

Binding Specificity: N-Term

Purpose: Anti-SKA2 Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human SKA2, which shares 90.0% amino acid (aa) sequence identity with both mouse and rat SKA2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for FAM33A

Target: FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))

Alternative Name: SKA2

Background:

Background: Spindle and kinetochore-associated protein 2 is a protein that in humans is encoded by the SKA2 gene found in chromosome 17.SKA2 is a part of a spindle and kinetochore associated complex also including SKA1 and SKA3 which is responsible for onset of the anaphase in mitosis by regulating chromosomal segregation. SKA2 may function as a prognostic gene marker for identifying lung cancer[3] as well as a proposed biomarker for suicidal tendencies and post-traumatic stress disorders.[4][5] The SKA2 gene contains one single-nucleotide polymorphism (SNP) rs7208505 located in the 3' UTR. This genetic variant containing a cytosine (existing in the less common allele) instead of thymine along with epigenetic modification (such as DNA methylation) is correlated with suicidal tendencies and post-traumatic stress

Gene Full Name: spindle and kinetochore associated complex subunit 2

Gene ID: 348235

UniProt: Q8WVK7

Pathways: M Phase