SPRED1 antibody (AA 45-322) (Fluoro647)

Catalog No. ABIN8042026

The Fluoro647-conjugated Rabbit Polyclonal anti-SPRED1 antibody (ABIN8042026) specifically detects SPRED1 in FACS. The antibody is reactive with Human samples.

Quick Overview for SPRED1 antibody (AA 45-322) (Fluoro647) (ABIN8042026)

Target: SPRED1 (Sprouty-Related, EVH1 Domain Containing 1 (SPRED1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPRED1 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-SPRED1 Antibody (Fluoro647)

Binding Specificity: AA 45-322

Purpose: Anti-SPRED1 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human SPRED1 shares 89.9% amino acid (aa) sequence identity with mouse SPRED1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SPRED1 recombinant protein (Position: F45-K322). Human SPRED1 shares 89.9% amino acid (aa) sequence identity with mouse SPRED1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SPRED1

Target: SPRED1 (Sprouty-Related, EVH1 Domain Containing 1 (SPRED1))

Alternative Name: SPRED1

Background:

Background: The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS).

Gene Full Name: sprouty related EVH1 domain containing 1

Gene ID: 161742

UniProt: Q7Z699

Pathways: Positive Regulation of Response to DNA Damage Stimulus