SOX1 antibody (Middle Region) (HRP)

Catalog No. ABIN8042190

The Rabbit Polyclonal anti-SOX1 antibody is suitable to detect SOX1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for SOX1 antibody (Middle Region) (HRP) (ABIN8042190)

Target: SOX1 (SRY (Sex Determining Region Y)-Box 1 (SOX1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SOX1 Antibody (HRP)

Binding Specificity: Middle Region

Purpose: Anti-SOX1 Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: identical to the related mouse sequence.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of Human SOX1, identical to the related mouse sequence.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SOX1

Target: SOX1 (SRY (Sex Determining Region Y)-Box 1 (SOX1))

Alternative Name: SOX1

Background:

Background: SOX1 (for Sex determining region Y-box 1), located in 13q34, is a transcription factor in the Sox protein family. It means that this intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. SOX1 expression is restricted to neuroectodermin the tetrapod embryo. It is expressed particularly in the ventral striatum.

Gene Full Name: SRY-box transcription factor 1

Sequence Similarities: Belongs to the Cu-Zn superoxide dismutase family.

Gene ID: 6656

UniProt: O00570