STARD10 antibody (AA 1-273) (FITC)

Catalog No. ABIN8042567

This Rabbit Polyclonal antibody specifically detects STARD10 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for STARD10 antibody (AA 1-273) (FITC) (ABIN8042567)

Target: STARD10 (StAR-Related Lipid Transfer (START) Domain Containing 10 (STARD10))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STARD10 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-STARD10 Antibody (FITC)

Binding Specificity: AA 1-273

Purpose: Anti-PCTP-L/STARD10 Antibody FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PCTP-L/STARD10 recombinant protein (Position: M1-E273).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for STARD10

Target: STARD10 (StAR-Related Lipid Transfer (START) Domain Containing 10 (STARD10))

Alternative Name: STARD10

Background:

Background: StAR-related lipid transfer protein 10 (STARD10) or PCTP-like protein is a lipid transfer protein that in humans is encoded by the STARD10 gene. StarD10 is a dual-specificity lipid transfer protein capable of shuttling phosphatidylcholine (PC) and phosphatidylethanolamine (PE) between membranes in vitro, changes in membrane composition of PC and PE occur before the morphological tumorigenic events. Interestingly, STARD10 has been described to be highly expressed in 35-40 % of ERBB2-positive breast cancers. StarD10 was initially discovered based on its cross-reactivity with a phosphoserine-specific antibody in mammary tumors from Neu/ErbB2 transgenic mice and subsequently isolated from SKBR3 human breast carcinoma cells using a multistep biochemical purification strategy. StarD10 contains a steroidogenic acute regulatory protein (StAR/StarD1)-related lipid transfer (START) domain that is thought to mediate binding of lipids. STARD10 is highly expressed in the liver and has been shown to transfer phosphatidylcholine.

Gene Full Name: StAR related lipid transfer domain containing 10

Gene ID: 10809

UniProt: Q9Y365