STS antibody (AA 297-396) (Fluoro488)

Catalog No. ABIN8042776

The Fluoro488-conjugated Rabbit Polyclonal anti-STS antibody (ABIN8042776) specifically detects STS in FACS. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for STS antibody (AA 297-396) (Fluoro488) (ABIN8042776)

Target: STS (Steroid Sulfatase (Microsomal), Isozyme S (STS))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STS antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-STS Antibody (Fluoro488)

Binding Specificity: AA 297-396

Purpose: Anti-Steroid sulfatase/STS Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Steroid sulfatase recombinant protein (Position: K297-E396).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for STS

Target: STS (Steroid Sulfatase (Microsomal), Isozyme S (STS))

Alternative Name: STS

Background:

Background: Steroid sulfatase (STS), or steryl-sulfatase, formerly known as arylsulfatase C, is a sulfatase enzyme involved in the metabolism of steroids. It is encoded by the STS gene. This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. Mutations in this gene are associated with X-linked ichthyosis (XLI). Alternatively spliced transcript variants resulting from the use of different promoters have been described for this gene.

Gene Full Name: steroid sulfatase

Gene ID: 412

UniProt: P08842

Pathways: Steroid Hormone Biosynthesis