SCP2 antibody (AA 33-547) (Fluoro488)

Catalog No. ABIN8042820

The Rabbit Polyclonal anti-SCP2 antibody is suitable to detect SCP2 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for SCP2 antibody (AA 33-547) (Fluoro488) (ABIN8042820)

Target: SCP2 (Sterol Carrier Protein 2 (SCP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCP2 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-SCP2 Antibody (Fluoro488)

Binding Specificity: AA 33-547

Purpose: Anti-SCP2 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human SCP2 shares 90.5%,88% amino acid (aa) sequence identity with mouse,rat SCP2,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SCP2 recombinant protein (Position: R33-L547). Human SCP2 shares 90.5% and 88% amino acid (aa) sequence identity with mouse and rat SCP2, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SCP2

Target: SCP2 (Sterol Carrier Protein 2 (SCP2))

Alternative Name: SCP2

Background:

Background: This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.

Gene Full Name: sterol carrier protein 2

Gene ID: 6342

UniProt: P22307

Pathways: C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process