STRA8 antibody (C-Term) (Fluoro550)

Catalog No. ABIN8042854

The Fluoro550-conjugated Rabbit Polyclonal anti-STRA8 antibody (ABIN8042854) specifically detects STRA8 in FACS. The antibody is reactive with Rat samples.

Quick Overview for STRA8 antibody (C-Term) (Fluoro550) (ABIN8042854)

Target: STRA8 (Stimulated By Retinoic Acid 8 (STRA8))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STRA8 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-STRA8 Antibody (Fluoro550)

Binding Specificity: C-Term

Purpose: Anti-Stra8 Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by one amino acid.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of rat Stra8, different from the related mouse sequence by one amino acid.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for STRA8

Target: STRA8 (Stimulated By Retinoic Acid 8 (STRA8))

Alternative Name: STRA8

Background:

Background: Stra8, stimulated by retinoic acid 8, is expressed in embryonic ovaries just before meiotic initiation, whereas in testis it is expressed after birth. The STRA8 gene contains 9 exons. And this gene is mapped to chromosome 7q31. Retinoic acid (RA) signaling was required for Stra8 expression, and therefore initiation of meiosis, in embryonic mouse ovaries. RA was sufficient to induce Stra8 expression in embryonic testis. Cyp26-mediated RA metabolism was responsible for delaying Stra8 expression in embryonic testis. Since RA signaling regulated Stra8 expression in both embryonic ovaries and adult testis, it was said this portion of the meiotic initiation pathway may be identical in both sexes.

Gene Full Name: stimulated by retinoic acid 8

Sequence Similarities: Contains 1 Ig-like C2-type (immunoglobulin-like) domain.

Gene ID: 500079

UniProt: D4ADQ4