STRIP2 antibody (AA 173-507) (PE)

Catalog No. ABIN8043036

The Rabbit Polyclonal anti-STRIP2 antibody is suitable to detect STRIP2 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for STRIP2 antibody (AA 173-507) (PE) (ABIN8043036)

Target: STRIP2 (Striatin Interacting Protein 2 (STRIP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STRIP2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-STRIP2 Antibody (PE)

Binding Specificity: AA 173-507

Purpose: Anti-FAM40B/STRIP2 Antibody PE Conjugated

Predicted Reactivity: Human STRIP2 shares 96.4% amino acid (aa) sequence identity with mouse STRIP2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FAM40B/STRIP2 recombinant protein (Position: H173-Q507). Human STRIP2 shares 96.4% amino acid (aa) sequence identity with mouse STRIP2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for STRIP2

Target: STRIP2 (Striatin Interacting Protein 2 (STRIP2))

Alternative Name: STRIP2

Background:

Background: The STRIP2 gene encodes a protein known as striatin-interacting protein 2, which interacts with striatin, a scaffolding protein involved in diverse cellular processes such as signaling, cell adhesion, and transcriptional regulation. STRIP2 is implicated in cardiac development and function, where it modulates cardiac hypertrophy, contractility, and arrhythmogenesis. Additionally, it plays roles in neuronal development and synaptic plasticity in the brain. Dysregulation of STRIP2 expression or function has been associated with various cardiovascular disorders, including hypertrophic cardiomyopathy and arrhythmias, as well as neurodevelopmental disorders such as autism spectrum disorders. Elucidating the molecular mechanisms underlying STRIP2 function is essential for understanding its physiological roles in cardiac and neural tissues and its potential implications for disease pathology and therapeutic targeting.

Gene Full Name: striatin interacting protein 2

Gene ID: 57464

UniProt: Q9ULQ0