Stim2 antibody (AA 458-726) (Biotin)

Catalog No. ABIN8043116

This Rabbit Polyclonal antibody specifically detects Stim2 in WB, ELISA and IHC. It exhibits reactivity toward Human and Rat.

Quick Overview for Stim2 antibody (AA 458-726) (Biotin) (ABIN8043116)

Target: Stim2 (Stromal Interaction Molecule 2 (Stim2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Stim2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Stim2 Antibody (Biotin)

Binding Specificity: AA 458-726

Purpose: Anti-STIM2 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human STIM2 shares 89.2% amino acid (aa) sequence identity with mouse STIM2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human STIM2 recombinant protein (Position: L458-H726). Human STIM2 shares 89.2% amino acid (aa) sequence identity with mouse STIM2.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Stim2

Target: Stim2 (Stromal Interaction Molecule 2 (Stim2))

Alternative Name: STIM2

Background:

Background: Stromal interaction molecule 2 (STIM2) is a protein that in humans is encoded by the STIM2 gene. This gene is a member of the stromal interaction molecule (STIM) family and likely arose, along with related family member STIM1, from a common ancestral gene. The encoded protein functions to regulate calcium concentrations in the cytosol and endoplasmic reticulum, and is involved in the activation of plasma membrane Orai Ca(2+) entry channels. This gene initiates translation from a non-AUG (UUG) start site. A signal peptide is cleaved from the resulting protein. Multiple transcript variants result from alternative splicing.

Gene Full Name: stromal interaction molecule 2

Gene ID: 57620

UniProt: Q9P246

Pathways: TCR Signaling, BCR Signaling