Stim2 antibody (AA 458-726)

Catalog No. ABIN8043126

The Rabbit Polyclonal anti-Stim2 antibody is suitable to detect Stim2 in samples from Human and Rat. It has been validated for WB, ELISA, IF and ICC.

Quick Overview for Stim2 antibody (AA 458-726) (ABIN8043126)

Target: Stim2 (Stromal Interaction Molecule 2 (Stim2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Stim2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Grade: Carrier-free

Product Details anti-Stim2 Antibody

Binding Specificity: AA 458-726

Purpose: Anti-STIM2 Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human STIM2 shares 89.2% amino acid (aa) sequence identity with mouse STIM2.

Characteristics: Anti-STIM2 Antibody. Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human STIM2 recombinant protein (Position: L458-H726). Human STIM2 shares 89.2% amino acid (aa) sequence identity with mouse STIM2.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Stim2

Target: Stim2 (Stromal Interaction Molecule 2 (Stim2))

Alternative Name: STIM2

Background:

Background: Stromal interaction molecule 2 (STIM2) is a protein that in humans is encoded by the STIM2 gene. This gene is a member of the stromal interaction molecule (STIM) family and likely arose, along with related family member STIM1, from a common ancestral gene. The encoded protein functions to regulate calcium concentrations in the cytosol and endoplasmic reticulum, and is involved in the activation of plasma membrane Orai Ca(2+) entry channels. This gene initiates translation from a non-AUG (UUG) start site. A signal peptide is cleaved from the resulting protein. Multiple transcript variants result from alternative splicing.

Gene Full Name: stromal interaction molecule 2

Molecular Weight: 98,100 kDa

Gene ID: 57620

UniProt: Q9P246

Pathways: TCR Signaling, BCR Signaling