SAE1 antibody (AA 33-299) (Fluoro488)

Catalog No. ABIN8043448

The Fluoro488-conjugated Rabbit Polyclonal anti-SAE1 antibody (ABIN8043448) specifically detects SAE1 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SAE1 antibody (AA 33-299) (Fluoro488) (ABIN8043448)

Target: SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAE1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-SAE1 Antibody (Fluoro488)

Binding Specificity: AA 33-299

Purpose: Anti-SAE1 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SAE1 recombinant protein (Position: R33-M299).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SAE1

Target: SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))

Alternative Name: SAE1

Background:

Background: SUMO-activating enzyme subunit 1 is a protein that in humans is encoded by the SAE1 gene. Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1, MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins.

Gene Full Name: SUMO1 activating enzyme subunit 1

Gene ID: 10055

UniProt: Q9UBE0