SURF1 antibody (AA 27-295) (Fluoro594)

Catalog No. ABIN8043903

The Rabbit Polyclonal anti-SURF1 antibody is suitable to detect SURF1 in samples from Human, Rat, Mouse and Monkey. It has been validated for FACS.

Quick Overview for SURF1 antibody (AA 27-295) (Fluoro594) (ABIN8043903)

Target: SURF1 (Surfeit 1 (SURF1))

Reactivity: Human, Rat, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SURF1 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-SURF1 Antibody (Fluoro594)

Binding Specificity: AA 27-295

Purpose: Anti-SURF1 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SURF1 recombinant protein (Position: S27-R295).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SURF1

Target: SURF1 (Surfeit 1 (SURF1))

Alternative Name: SURF1

Background:

Background: Surfeit locus protein 1 (SURF1) is a protein that in humans is encoded by the SURF1 gene. This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a biional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.

Gene Full Name: SURF1 cytochrome c oxidase assembly factor

Gene ID: 6834

UniProt: Q15526

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process