Symplekin antibody (AA 384-1092)

Catalog No. ABIN8044206

The Rabbit Polyclonal anti-Symplekin antibody is suitable to detect Symplekin in samples from Human and Rat. It has been validated for WB, IHC, ELISA, IF, FACS and ICC.

Quick Overview for Symplekin antibody (AA 384-1092) (ABIN8044206)

Target: Symplekin (SYMPK)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Symplekin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Grade: Carrier-free

Product Details anti-Symplekin Antibody

Binding Specificity: AA 384-1092

Purpose: Anti-Symplekin/SYMPK Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Symplekin/SYMPK Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Symplekin/SYMPK recombinant protein (Position: K384-N1092).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Symplekin

Target: Symplekin (SYMPK)

Alternative Name: SYMPK

Background:

Background: Symplekin is a protein that in humans is encoded by the SYMPK gene. This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types.

Gene Full Name: symplekin scaffold protein

Molecular Weight: 150 kDa

Gene ID: 8189

UniProt: Q92797