SYN2 antibody (AA 497-582) (Fluoro647)

Catalog No. ABIN8044250

This Rabbit Polyclonal antibody specifically detects SYN2 in FACS. It exhibits reactivity toward Mouse, Human, Rat and Pig.

Quick Overview for SYN2 antibody (AA 497-582) (Fluoro647) (ABIN8044250)

Target: SYN2 (Synapsin II (SYN2))

Reactivity: Mouse, Human, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYN2 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-SYN2 Antibody (Fluoro647)

Binding Specificity: AA 497-582

Purpose: Anti-Synapsin II/SYN2 Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human Synapsin II recombinant protein (Position: A497-D582). Human Synapsin II shares 93.1%,89.7% amino acid (aa) sequence identity with mouse,rat Synapsin II,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Synapsin II recombinant protein (Position: A497-D582). Human Synapsin II shares 93.1% and 89.7% amino acid (aa) sequence identity with mouse and rat Synapsin II, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SYN2

Target: SYN2 (Synapsin II (SYN2))

Alternative Name: SYN2

Background:

Background: Synapsin II is the collective name for synapsin IIa and synapsin IIb, two nearly identical phosphoproteins in the synapsin family that in humans are encoded by the SYN2 gene. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. Polymorphisms in this gene are associated with abnormal presynaptic function and related neuronal disorders, including autism, epilepsy, bipolar disorder and schizophrenia. Alternative splicing of this gene results in multiple transcript variants. The tissue inhibitor of metalloproteinase 4 gene is located within an intron of this gene and is transcribed in the opposite ion.

Gene Full Name: synapsin II

Gene ID: 6854

UniProt: Q92777