SYN2 antibody (AA 497-582)

Catalog No. ABIN8044251

The Rabbit Polyclonal anti-SYN2 antibody is suitable to detect SYN2 in samples from Mouse, Human, Rat and Pig. It has been validated for WB, IHC, IF and ICC.

Quick Overview for SYN2 antibody (AA 497-582) (ABIN8044251)

Target: SYN2 (Synapsin II (SYN2))

Reactivity: Mouse, Human, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Grade: Carrier-free

Product Details anti-SYN2 Antibody

Binding Specificity: AA 497-582

Purpose: Anti-Synapsin II/SYN2 Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human Synapsin II recombinant protein (Position: A497-D582). Human Synapsin II shares 93.1%,89.7% amino acid (aa) sequence identity with mouse,rat Synapsin II,respectively.

Characteristics: Anti-Synapsin II/SYN2 Antibody. Tested in ICC/IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat, Pig.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Synapsin II recombinant protein (Position: A497-D582). Human Synapsin II shares 93.1% and 89.7% amino acid (aa) sequence identity with mouse and rat Synapsin II, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Pig, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SYN2

Target: SYN2 (Synapsin II (SYN2))

Alternative Name: SYN2

Background:

Background: Synapsin II is the collective name for synapsin IIa and synapsin IIb, two nearly identical phosphoproteins in the synapsin family that in humans are encoded by the SYN2 gene. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. Polymorphisms in this gene are associated with abnormal presynaptic function and related neuronal disorders, including autism, epilepsy, bipolar disorder and schizophrenia. Alternative splicing of this gene results in multiple transcript variants. The tissue inhibitor of metalloproteinase 4 gene is located within an intron of this gene and is transcribed in the opposite ion.

Gene Full Name: synapsin II

Molecular Weight: 55, 80 kDa

Gene ID: 6854

UniProt: Q92777