SDC3 antibody (N-Term) (Fluoro550)

Catalog No. ABIN8044663

The Fluoro550-conjugated Rabbit Polyclonal anti-SDC3 antibody (ABIN8044663) specifically detects SDC3 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SDC3 antibody (N-Term) (Fluoro550) (ABIN8044663)

Target: SDC3 (Syndecan 3 (SDC3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDC3 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-SDC3 Antibody (Fluoro550)

Binding Specificity: N-Term

Purpose: Anti-Syndecan 3/SDC3 Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: identical to the related rat sequence,and different from the related human sequence by one amino acid.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse Syndecan 3/SDC3, identical to the related rat sequence, and different from the related human sequence by one amino acid.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SDC3

Target: SDC3 (Syndecan 3 (SDC3))

Alternative Name: SDC3

Background:

Background: Syndecan-3, also called SYND3 is a protein that in humans is encoded by the SDC3 gene. This gene was assigned to human chromosome 1p35.2. This gene can function as in trans HIV receptors via binding of HIV-1 gp120 to the syndecan heparin sulfate chains. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, and possibly by transferring signals from the cell surface in a sugar-dependent mechanism. In wildtype mice, SDC3 was expressed in hypothalamic regions that control energy balance. It was proposed that oscillation of hypothalamic SDC3 levels physiologically modulates feeding behavior.

Gene Full Name: syndecan 3

Sequence Similarities: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

Gene ID: 20970

UniProt: Q64519

Pathways: Glycosaminoglycan Metabolic Process