SDC4 antibody (C-Term) (Cy3)

Catalog No. ABIN8044672

The Cy3-conjugated Rabbit Polyclonal anti-SDC4 antibody (ABIN8044672) specifically detects SDC4 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SDC4 antibody (C-Term) (Cy3) (ABIN8044672)

Target: SDC4 (Syndecan 4 (SDC4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDC4 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-SDC4 Antibody (Cy3)

Binding Specificity: C-Term

Purpose: Anti-Syndecan 4/SDC4 Antibody Cy3 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Syndecan 4, identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SDC4

Target: SDC4 (Syndecan 4 (SDC4))

Alternative Name: SDC4

Background:

Background: Syndecan 4 is also known as SDC4. The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Gene Full Name: syndecan 4

Gene ID: 6385

UniProt: P31431

Pathways: Glycosaminoglycan Metabolic Process