SYNM antibody (AA 93-1554) (Fluoro647)

Catalog No. ABIN8044713

The Rabbit Polyclonal anti-SYNM antibody is suitable to detect SYNM in samples from Human and Mouse. It has been validated for FACS.

Quick Overview for SYNM antibody (AA 93-1554) (Fluoro647) (ABIN8044713)

Target: SYNM (Synemin, Intermediate Filament Protein (SYNM))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYNM antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-SYNM Antibody (Fluoro647)

Binding Specificity: AA 93-1554

Purpose: Anti-SYNM Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human SYNM shares 68.1% amino acid (aa) sequence identity with mouse SYNM.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SYNM recombinant protein (Position: R93-D1554). Human SYNM shares 68.1% amino acid (aa) sequence identity with mouse SYNM.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SYNM

Target: SYNM (Synemin, Intermediate Filament Protein (SYNM))

Alternative Name: SYNM

Background:

Background: Synemin, also known as desmuslin, is a protein that in humans is encoded by the SYNM gene. The protein encoded by this gene is an intermediate filament (IF) family member. IF proteins are cytoskeletal proteins that confer resistance to mechanical stress and are encoded by a dispersed multigene family. This protein has been found to form a linkage between desmin, which is a subunit of the IF network, and the extracellular matrix, and provides an important structural support in muscle. Two alternatively spliced variants encoding different isoforms have been described for this gene.

Gene Full Name: synemin

Gene ID: 23336

UniProt: O15061