Syntaxin 4 antibody (AA 1-278) (Fluoro647)

Catalog No. ABIN8044823

This Rabbit Polyclonal antibody specifically detects Syntaxin 4 in FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Syntaxin 4 antibody (AA 1-278) (Fluoro647) (ABIN8044823)

Target: Syntaxin 4 (STX4)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syntaxin 4 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-Syntaxin 4 Antibody (Fluoro647)

Binding Specificity: AA 1-278

Purpose: Anti-Syntaxin 4/STX4 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human Syntaxin 4,STX4 shares 91.7%,91.4% amino acid (aa) sequence identity with mouse,rat Syntaxin 4,STX4,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Syntaxin 4/STX4 recombinant protein (Position: M1-I278). Human Syntaxin 4/STX4 shares 91.7% and 91.4% amino acid (aa) sequence identity with mouse and rat Syntaxin 4/STX4, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Syntaxin 4

Target: Syntaxin 4 (STX4)

Alternative Name: STX4

Background:

Background: Enables sphingomyelin phosphodiesterase activator activity. Involved in several processes, including cornified envelope assembly, positive regulation of immune effector process, and positive regulation of protein localization. Located in several cellular components, including basolateral plasma membrane, cytoplasmic vesicle, and lamellipodium. Part of SNARE complex. Is active in glutamatergic synapse and postsynapse. Implicated in autosomal recessive nonsyndromic deafness.

Gene Full Name: syntaxin 4

Gene ID: 6810

UniProt: Q12846

Pathways: Synaptic Vesicle Exocytosis