Syntaxin 5 antibody (AA 1-327) (PE)

Catalog No. ABIN8044833

The Rabbit Polyclonal anti-Syntaxin 5 antibody is suitable to detect Syntaxin 5 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for Syntaxin 5 antibody (AA 1-327) (PE) (ABIN8044833)

Target: Syntaxin 5 (STX5)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syntaxin 5 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-Syntaxin 5 Antibody (PE)

Binding Specificity: AA 1-327

Purpose: Anti-STX5 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human STX5 shares 93.6%,94.5% amino acid (aa) sequence identity with mouse,rat STX5,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human STX5 recombinant protein (Position: M1-Q327). Human STX5 shares 93.6% and 94.5% amino acid (aa) sequence identity with mouse and rat STX5, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Syntaxin 5

Target: Syntaxin 5 (STX5)

Alternative Name: STX5

Background:

Background: This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: syntaxin 5

Gene ID: 6811

UniProt: Q13190

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size, Synaptic Vesicle Exocytosis