TNIK antibody (AA 1281-1360) (Biotin)
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- Target See all TNIK Antibodies
- TNIK (TRAF2 and NCK Interacting Kinase (TNIK))
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Binding Specificity
- AA 1281-1360
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TNIK antibody is conjugated to Biotin
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Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Mouse, Rat
- Predicted Reactivity
- Human,Cow,Pig,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human TNIK
- Isotype
- IgG
- Top Product
- Discover our top product TNIK Primary Antibody
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- Application Notes
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IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- TNIK (TRAF2 and NCK Interacting Kinase (TNIK))
- Alternative Name
- TNIK (TNIK Products)
- Synonyms
- RGD1561817 antibody, TNIK antibody, 1500031A17Rik antibody, 4831440I19Rik antibody, AI451411 antibody, C530008O15Rik antibody, C630040K21Rik antibody, fc52d11 antibody, msn antibody, tnikl antibody, wu:fc52d11 antibody, zgc:63535 antibody, im:6898857 antibody, zgc:123033 antibody, zgc:152783 antibody, tnik antibody, TRAF2 and NCK interacting kinase antibody, TRAF2 and NCK interacting kinase a antibody, TRAF2 and NCK interacting kinase b antibody, TRAF2 and NCK interacting kinase S homeolog antibody, TNIK antibody, Tnik antibody, tnika antibody, tnikb antibody, tnik.S antibody
- Background
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Synonyms: Traf2 and NCK interacting kinase, 1500031A17RIK, 4831440I19RIK, AI451411, C530008O15Rik, C630040K21RIK, KIAA0551, MGC189819, MGC189859, RGD1561817, TNIK, TNIK_HUMAN, TRAF2 and NCK-interacting protein kinase.
Background: TNIK is a MSN protein kinase that interacts with both TNF receptor-associated factor 2 (TRAF2) and the adapter protein NCK. The protein has been shown to activate the c-Jun N-terminal kinase pathway when over expressed in Phoenix-A cells. TNIK has been shown to phosphorylate gelsolin, the principal intracellular and extracellular actin-severing protein, in vitro. This and evidence from mutational studies suggest that TNIK functions in the regulation of the cytoskeleton. Northern analysis indicates TNIK expression in human heart, skeletal muscle, and brain, with lower levels of expression in kidney, liver, lung, and pancreas. ESTs have been isolated from human tissue libraries, including normal amnion, gallbladder and skin.
- Gene ID
- 23043
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