TBR1 antibody (AA 15-682) (PE)

Catalog No. ABIN8045076

The Rabbit Polyclonal anti-TBR1 antibody is suitable to detect TBR1 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for TBR1 antibody (AA 15-682) (PE) (ABIN8045076)

Target: TBR1 (T-Box Brain Gene 1 (TBR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBR1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-TBR1 Antibody (PE)

Binding Specificity: AA 15-682

Purpose: Anti-TBR1 Antibody PE Conjugated

Predicted Reactivity: Human TBR1 shares 99.3% amino acid (aa) sequence identity with mouse TBR1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TBR1 recombinant protein (Position: K15-S682). Human TBR1 shares 99.3% amino acid (aa) sequence identity with mouse TBR1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TBR1

Target: TBR1 (T-Box Brain Gene 1 (TBR1))

Alternative Name: TBR1

Background:

Background: T-box, brain, 1 is a transcription factor protein important in vertebrate embryo development. It is encoded by the TBR1 gene. This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of numerous developmental processes. In mouse, the ortholog of this gene is expressed in the cerebral cortex, hippocampus, amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection. In mouse, the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.

Gene Full Name: T-box brain transcription factor 1

Gene ID: 10716

UniProt: Q16650