DR1 antibody (AA 7-154) (FITC)

Catalog No. ABIN8045513

This Rabbit Polyclonal antibody specifically detects DR1 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for DR1 antibody (AA 7-154) (FITC) (ABIN8045513)

Target: DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DR1 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-DR1 Antibody (FITC)

Binding Specificity: AA 7-154

Purpose: Anti-DR1 Antibody FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DR1 recombinant protein (Position: N7-A154).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for DR1

Target: DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

Alternative Name: DR1

Background:

Background: Protein Dr1 is a protein that in humans is encoded by the DR1 gene. This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.

Gene Full Name: down-regulator of transcription 1

Gene ID: 1810

UniProt: Q01658