TTBK1 antibody (AA 285-956) (Biotin)

Catalog No. ABIN8045519

This Rabbit Polyclonal antibody specifically detects TTBK1 in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TTBK1 antibody (AA 285-956) (Biotin) (ABIN8045519)

Target: TTBK1 (tau Tubulin Kinase 1 (TTBK1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTBK1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-TTBK1 Antibody (Biotin)

Binding Specificity: AA 285-956

Purpose: Anti-TTBK1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TTBK1 shares 92.6% amino acid (aa) sequence identity with mouse TTBK1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TTBK1 recombinant protein (Position: D285-A956). Human TTBK1 shares 92.6% amino acid (aa) sequence identity with mouse TTBK1.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TTBK1

Target: TTBK1 (tau Tubulin Kinase 1 (TTBK1))

Alternative Name: TTBK1

Background:

Background: Summary:This gene belongs to the casein kinase 1 superfamily. The encoded protein is a neuron-specific, serine/threonine and tyrosine kinase, which regulates phosphorylation of tau, a protein that associates with microtubule assemblies and stabilizes them. Genetic variants in this gene are associated with Alzheimer's disease.

Gene Full Name: tau tubulin kinase 1

Gene ID: 84630

UniProt: Q5TCY1