TCTN1 antibody (AA 118-470) (Fluoro594)

Catalog No. ABIN8045644

The Fluoro594-conjugated Rabbit Polyclonal anti-TCTN1 antibody (ABIN8045644) specifically detects TCTN1 in FACS. The antibody is reactive with Rat, Human and Mouse samples.

Quick Overview for TCTN1 antibody (AA 118-470) (Fluoro594) (ABIN8045644)

Target: TCTN1 (Tectonic Family Member 1 (TCTN1))

Reactivity: Rat, Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCTN1 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-TCTN1 Antibody (Fluoro594)

Binding Specificity: AA 118-470

Purpose: Anti-TCTN1 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TCTN1 shares 68.6% amino acid (aa) sequence identity with mouse TCTN1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TCTN1 recombinant protein (Position: Q118-Y470). Human TCTN1 shares 68.6% amino acid (aa) sequence identity with mouse TCTN1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TCTN1

Target: TCTN1 (Tectonic Family Member 1 (TCTN1))

Alternative Name: TCTN1

Background:

Background: This gene encodes a member of a family of secreted and transmembrane proteins. The orthologous gene in mouse functions downstream of smoothened and rab23 to modulate hedgehog signal transduction. This protein is a component of the tectonic-like complex, which forms a barrier between the ciliary axoneme and the basal body. A mutation in this gene was found in a family with Joubert syndrome-13. Alternative splicing results in multiple transcript variants.

Gene Full Name: tectonic family member 1

Gene ID: 79600

UniProt: Q2MV58

Pathways: Tube Formation