Tenascin R antibody (AA 60-1007)

Catalog No. ABIN8045760

The Rabbit Polyclonal anti-Tenascin R antibody is suitable to detect Tenascin R in samples from Human, Rat and Mouse. It has been validated for ELISA and WB.

Quick Overview for Tenascin R antibody (AA 60-1007) (ABIN8045760)

Target: Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tenascin R antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Grade: Carrier-free

Product Details anti-Tenascin R Antibody

Binding Specificity: AA 60-1007

Purpose: Anti-Tenascin-R/TNR Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human TNR shares 94.2%,93.6% amino acid (aa) sequence identity with mouse,rat TNR,respectively.

Characteristics: Anti-Tenascin-R/TNR Antibody. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Tenascin-R/TNR recombinant protein (Position: E60-R1007). Human TNR shares 94.2% and 93.6% amino acid (aa) sequence identity with mouse and rat TNR, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Tenascin R

Target: Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))

Alternative Name: TNR

Background:

Background: Tenascin-R is a protein that in humans is encoded by the TNR gene. Tenascin-R(TNR) is an extracellular matrix protein expressed primarily in the central nervous system. It is a member of the tenascin(TN) gene family, which includes at least 3 genes in mammals: TNC(or hexabrachion), TNX(TNXB), and TNR. The genes are expressed in distinct tissues at different times during embryonic development and are present in adult tissues. TNR has been detected predominantly in the central nervous system and is localized around motor neurons and on motor axons in the spinal cord, cerebellum, hippocampus, and olfactory bulb. It is suggested that tenascin-R has a role in initiating the detachment of neuroblasts from tangential chains and in initiating radial migration of the cells.

Gene Full Name: tenascin R

Molecular Weight: 180 kDa

Gene ID: 7143

UniProt: Q92752

Pathways: Regulation of Cell Size