Thymic Stromal Lymphopoietin antibody (C-Term) (HRP)

Catalog No. ABIN8046484

The HRP-conjugated Rabbit Polyclonal anti-Thymic Stromal Lymphopoietin antibody (ABIN8046484) specifically detects Thymic Stromal Lymphopoietin in WB, IHC and ELISA. The antibody is reactive with Mouse and Rat samples.

Quick Overview for Thymic Stromal Lymphopoietin antibody (C-Term) (HRP) (ABIN8046484)

Target: Thymic Stromal Lymphopoietin (TSLP)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Thymic Stromal Lymphopoietin antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Thymic Stromal Lymphopoietin Antibody (HRP)

Binding Specificity: C-Term

Purpose: Anti-TSLP Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse TSLP, which shares 76.2% amino acid (aa) sequence identity with rat TSLP.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Thymic Stromal Lymphopoietin

Target: Thymic Stromal Lymphopoietin (TSLP)

Alternative Name: Tslp

Background:

Background: Thymic stromal lymphopoietin, also called TSLP is a protein belonging to the cytokine family. This gene is mapped to 5q22.1. It encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c (+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases.

Gene Full Name: thymic stromal lymphopoietin

Gene ID: 53603

UniProt: Q9JIE6