TIMELESS antibody (AA 72-1050) (Fluoro647)

Catalog No. ABIN8046817

The Fluoro647-conjugated Rabbit Polyclonal anti-TIMELESS antibody (ABIN8046817) specifically detects TIMELESS in FACS. The antibody is reactive with Human samples.

Quick Overview for TIMELESS antibody (AA 72-1050) (Fluoro647) (ABIN8046817)

Target: TIMELESS (Timeless Homolog (TIMELESS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMELESS antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-TIMELESS Antibody (Fluoro647)

Binding Specificity: AA 72-1050

Purpose: Anti-TIMELESS Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TIMELESS recombinant protein (Position: Q72-E1050).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TIMELESS

Target: TIMELESS (Timeless Homolog (TIMELESS))

Alternative Name: TIMELESS

Background:

Background: The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the PERIOD genes (PER1, PER2, and PER3) and others to downregulate activation of PER1 by CLOCK/ARNTL. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders.

Gene Full Name: timeless circadian regulator

Gene ID: 8914

UniProt: Q9UNS1

Pathways: Protein targeting to Nucleus, Photoperiodism