TIMP1 antibody (C-Term) (Fluoro594)

Catalog No. ABIN8046856

The Fluoro594-conjugated Rabbit Polyclonal anti-TIMP1 antibody (ABIN8046856) specifically detects TIMP1 in FACS. The antibody is reactive with Human samples.

Quick Overview for TIMP1 antibody (C-Term) (Fluoro594) (ABIN8046856)

Target: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMP1 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-TIMP1 Antibody (Fluoro594)

Binding Specificity: C-Term

Purpose: Anti-Metalloproteinase inhibitor 1 TIMP1 Antibody Fluoro594 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TIMP-1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TIMP1

Target: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Alternative Name: TIMP1

Background:

Background: TIMP metallopeptidase inhibitor 1, also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. This protein a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. TIMP was found to be located about 22 cM proximal to OTC (300461).

Gene Full Name: TIMP metallopeptidase inhibitor 1

Sequence Similarities: Belongs to the protease inhibitor I35 (TIMP) family.

Gene ID: 7076

UniProt: P01033