TRAF5 antibody (N-Term)

Catalog No. ABIN8047148

This Rabbit Polyclonal antibody specifically detects TRAF5 in WB. It exhibits reactivity toward Human.

Quick Overview for TRAF5 antibody (N-Term) (ABIN8047148)

Target: TRAF5 (TNF Receptor-Associated Factor 5 (TRAF5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAF5 antibody is un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Product Details anti-TRAF5 Antibody

Binding Specificity: N-Term

Purpose: Anti-TRAF5 Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by two amino acids.

Characteristics: Anti-TRAF5 Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human TRAF5, different from the related mouse sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TRAF5

Target: TRAF5 (TNF Receptor-Associated Factor 5 (TRAF5))

Alternative Name: TRAF5

Background:

Background: TNF receptor-associated factor 5, also known as RNF84, is a protein that in humans is encoded by the TRAF5 gene. The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family. Fluorescence in situ hybridization confirmed the regional localization of human TRAF5 to chromosome 1q32.2-q32.3. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. It is an adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. It seems to be involved in apoptosis.

Gene Full Name: TNF receptor associated factor 5

Sequence Similarities: Belongs to the TNF receptor-associated factor family. A subfamily.

Molecular Weight: 18 kDa

Gene ID: 7188

UniProt: O00463

Pathways: NF-kappaB Signaling, Apoptosis