TRAF3IP2 antibody (AA 1-528) (FITC)

Catalog No. ABIN8047704

The Rabbit Polyclonal anti-TRAF3IP2 antibody is suitable to detect TRAF3IP2 in samples from Human, Rat and Mouse. It has been validated for FACS.

Quick Overview for TRAF3IP2 antibody (AA 1-528) (FITC) (ABIN8047704)

Target: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAF3IP2 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-TRAF3IP2 Antibody (FITC)

Binding Specificity: AA 1-528

Purpose: Anti-TRAF3IP2 Antibody FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TRAF3IP2 shares 77% amino acid (aa) sequence identity with mouse TRAF3IP2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TRAF3IP2 recombinant protein (Position: M1-H528). Human TRAF3IP2 shares 77% amino acid (aa) sequence identity with mouse TRAF3IP2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TRAF3IP2

Target: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Alternative Name: TRAF3IP2

Background:

Background: This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.

Gene Full Name: TRAF3 interacting protein 2

Gene ID: 10758

UniProt: O43734

Pathways: Production of Molecular Mediator of Immune Response